F

Agios Pharmaceuticals, Inc. — Earnings Quality Grade F

AGIO · Healthcare

Major red flags

Revenue
$54M
2025
Net Income
-$413M
2025
Gross Margin
88.3%
Free Cash Flow
-$387M
01

Screening Summary

8
Passed
4
Watch
5
Failed
-1.74
M-Score

Management Signals

No recent CEO, CFO, board, or accounting leadership signals found in SEC 8-K filings.
02

Financial Trends

Revenue & Net Income ($B)

Margins (%)

03

18-Point Screening

01

Revenue Quality

A1DSO Change

DSO surged by 30 days (41 → 71)

Small-cap context: DSO swings on a small revenue base are more often quarterly customer-mix effects than red flags.

A2AR vs Revenue Growth

AR outpaced revenue for 2 consecutive years

!
A3Revenue vs CFFO

Revenue grew 48.0% but CFFO only 4.3%

02

Expense Quality

B1Inventory vs COGS

Inventory 19.2% vs COGS 52.3%. Normal

!
B2CapEx vs Revenue

CapEx growth 749.6% is >2x revenue growth 48.0%

!
B3SG&A Ratio

SG&A/Gross Profit = 378.1%, exceeds 70%

B4Gross Margin

Gross margin 88.3%, change -0.3pp. Stable

03

Cash Flow Quality

C1CFFO vs Net Income

CFFO < Net Income for 3 consecutive years

Small-cap context: Small-cap CFFO/NI often diverges from working-capital swings, not necessarily manipulation.

!
C2Free Cash Flow

FCF is negative ($-0.4B)

C3Accruals Ratio

Accruals ratio = -3.1%. Low accruals

C4Cash vs Debt

Cash $0.9B covers debt $0.0B

04

Balance Sheet Health

D1Goodwill + Intangibles

No goodwill. Clean balance sheet

D2Leverage

Debt/EBITDA = -0.1x. Healthy

D3Soft Asset Growth

Other assets -16.8% vs revenue 48.0%. Normal

D4Asset Impairment

No write-off data

05

Acquisition Risk

E1Serial Acquirer FCF

FCF after acquisitions negative for 3 years

Small-cap context: A single acquisition on a small balance sheet can trip serial-acquirer logic.

E2Goodwill Surge

No goodwill

06

Manipulation Score

F1Beneish M-Score

M-Score = -1.74 (> -1.78). LIKELY MANIPULATOR

Small-cap context: Beneish M-Score was calibrated on large-caps; small-cap DSO/inventory volatility mechanically inflates it.

04

Beneish M-Score

Manipulation Probability-1.74
-4.0 Clean-2.22 Grey-1.78 Danger0
1.739
DSRI
AR growing faster than revenue?
1.004
GMI
Gross margin declining?
0.626
AQI
Asset quality deteriorating?
1.48
SGI
Revenue growth rate
0.842
DEPI
Depreciation slowing?
0.777
SGAI
SG&A ratio changing?
-0.0307
TATA
Accruals level
1.299
LVGI
Leverage increasing?
05

Altman Z-Score

12.52
Safe Zone
0 Distress1.102.605.0+ Safe
0.6628
Liquidity
-0.433
Cumulative profit
-0.364
Operating efficiency
11.46
Leverage

Generated from public financial data using forensic accounting frameworks. Not investment advice. Data: Yahoo Finance · 2026-04-25